Jaw stiffness and dental extractions due to pharmacodynamic interaction between mirtazapine and chlorpromazine

  • Patricia de Carvalho MASTROIANNI Universidade Estadual Paulista “Júlio de Mesquita Filho” https://orcid.org/0000-0001-8467-7278
  • Fabiana Rossi VARALLO Universidade Estadual Paulista “Júlio de Mesquita Filho” https://orcid.org/0000-0003-4016-1442
  • Manuel MACHUCA Unit of Optimization of the pharmacotherapy
Keywords: bruxism, serotonin syndrome, medication therapy management, pharmaceutical care

Abstract

A comprehensive assessment of the patient’s drug related needs allows identifying health problems drug-induced. It has been demonstrated that each dollar spent on clinical pharmacy services reduces the pooled median cost of health by 4.81 dollars. Jaw stiffness (bruxism) can be a serotonergic manifestation related to drugs with serotonin reuptake inhibition activity. Clinical manifestations also include: agitation, tachycardia, high blood pressure, tremor, fever, dyspnea, diarrhea, mental confusion and insomnia.

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Author Biographies

Patricia de Carvalho MASTROIANNI, Universidade Estadual Paulista “Júlio de Mesquita Filho”

School of Pharmacy and Pharmaceutical Sciences, Department of Drugs and Medications. PhD, Assistant Doctor Professor

Fabiana Rossi VARALLO, Universidade Estadual Paulista “Júlio de Mesquita Filho”
School of Pharmacy and Pharmaceutical Sciences, Department of Drugs and Medications. PhD Student
Manuel MACHUCA, Unit of Optimization of the pharmacotherapy
Clinical pharmacist. PhD in Pharmacy

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Published
2014-07-21
How to Cite
MASTROIANNI P. de C., VARALLO F. R., & MACHUCA M. (2014). Jaw stiffness and dental extractions due to pharmacodynamic interaction between mirtazapine and chlorpromazine. Vitae, 21(2), 146-147. Retrieved from https://revistas.udea.edu.co/index.php/vitae/article/view/16097
Section
Letter to Editor