Jaw stiffness and dental extractions due to pharmacodynamic interaction between mirtazapine and chlorpromazine

Authors

  • Patricia de Carvalho MASTROIANNI Universidade Estadual Paulista “Júlio de Mesquita Filho” https://orcid.org/0000-0001-8467-7278
  • Fabiana Rossi VARALLO Universidade Estadual Paulista “Júlio de Mesquita Filho” https://orcid.org/0000-0003-4016-1442
  • Manuel MACHUCA Unit of Optimization of the pharmacotherapy

DOI:

https://doi.org/10.17533/udea.vitae.16097

Keywords:

bruxism, serotonin syndrome, medication therapy management, pharmaceutical care

Abstract

A comprehensive assessment of the patient’s drug related needs allows identifying health problems drug-induced. It has been demonstrated that each dollar spent on clinical pharmacy services reduces the pooled median cost of health by 4.81 dollars. Jaw stiffness (bruxism) can be a serotonergic manifestation related to drugs with serotonin reuptake inhibition activity. Clinical manifestations also include: agitation, tachycardia, high blood pressure, tremor, fever, dyspnea, diarrhea, mental confusion and insomnia.

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Author Biographies

Patricia de Carvalho MASTROIANNI, Universidade Estadual Paulista “Júlio de Mesquita Filho”

School of Pharmacy and Pharmaceutical Sciences, Department of Drugs and Medications. PhD, Assistant Doctor Professor

Fabiana Rossi VARALLO, Universidade Estadual Paulista “Júlio de Mesquita Filho”

School of Pharmacy and Pharmaceutical Sciences, Department of Drugs and Medications. PhD Student

Manuel MACHUCA, Unit of Optimization of the pharmacotherapy

Clinical pharmacist. PhD in Pharmacy

References

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Published

21-07-2014

How to Cite

MASTROIANNI, P. de C., VARALLO, F. R., & MACHUCA, M. (2014). Jaw stiffness and dental extractions due to pharmacodynamic interaction between mirtazapine and chlorpromazine. Vitae, 21(2), 146–147. https://doi.org/10.17533/udea.vitae.16097

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Letter to Editor

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