Effect of parenteral nutrition intravenous lipids on platelet blood counting in term and preterm newborns

Authors

  • Carlos Alberto Velasco Benítez University of the Valley
  • Liliana Ladino Meléndez Pontificia Universidad Javeriana
  • Ángela Patricia Luna Medicis Pontificia Universidad Javeriana

DOI:

https://doi.org/10.17533/udea.penh.9413

Keywords:

parenteral nutrition, fat emulsions intravenous, thrombocytopenia, platelet count, infant newborn

Abstract

Introduction: Parenteral nutrition (NPT) support is another option in newborn when they cannot receive enteral nutrition. Thrombocytopenia has been reported as a complication for the use of NPT intravenous lipids. Objective: To evaluate the effect of NPT intravenous lipids on platelet blood counting in newborns. Materials and methods: this is a prospective study carried out in newborns requiring parenteral nutrition support who were hospitalized in Bucaramanga-Colombia. All patients received intravenous lipids. Doses were increasing of 0,5 g/kg/ day at the first day to reach 3 g/kg/day at the end. They were monitored daily and platelet blood counting was assessed at baseline and seven days later. Results: subjects were 22 term newborns and 29 preterm (55% men), they presenting different clinical conditions like prematurity (22), necrotic enterocolitis (17), respiratory problems (4), esophageal atresia (2) and others (6). The platelet blood counting showed no significant differences between baseline and the seventh day (p> 0.05), no in preterm (227.320±86290/mm3 versus 294.930±120.600/mm3), and either in the newborns (276.140±130.240/mm3 versus 273.240±96.890/mm3) no adverse effects were reported. Conclusion: administration of intravenous lipid at doses up to 3 g/ kg / day in term and preterm newborns is safe, and no thrombocytopenia was not reported and other adverse effects.
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Author Biographies

Carlos Alberto Velasco Benítez, University of the Valley

Gastrohnup Research Group. University of the Valley. Cali, Colombia.

Liliana Ladino Meléndez, Pontificia Universidad Javeriana

Pontificia Universidad Javeriana. Bogotá, Colombia.

Ángela Patricia Luna Medicis, Pontificia Universidad Javeriana

Pontificia Universidad Javeriana. Bogotá, Colombia.

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Published

2011-04-01

How to Cite

Velasco Benítez, C. A., Ladino Meléndez, L., & Luna Medicis, Ángela P. (2011). Effect of parenteral nutrition intravenous lipids on platelet blood counting in term and preterm newborns. Perspectivas En Nutrición Humana, 12(1), 25–32. https://doi.org/10.17533/udea.penh.9413

Issue

Vol. 12 No. 1 (2010)

Section

Research

License

Derechos de autor 2024 Universidad de Antioquia

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