An Approach to the Relationship Between Sleep and Cancer
DOI:
https://doi.org/10.17533/udea.iatreia.351Keywords:
Circadian Rhythm, Neoplasms, Sleep, Sleep Deprivation, Sleep QualityAbstract
Introduction: Sleep performs a restorative function in both human and other animal organisms, and it appears to have a bidirectional correlation with cancer. Disruptions in sleep and circadian cycles are implicated in the development and progression of these diseases, while cancer itself contributes to the onset of sleep disorders.
Objectives: To describe the bidirectional relationship between sleep and cancer in a narrative review.
Methods: A total of 181 articles published during the last decade in four scientific databases were reviewed.
Results: Sleep disturbances (e.g. deprivation due to shift work) are associated with the development and progression of cancer. At the same time, biological mechanisms of malignant neoplasms (e.g. inflammatory process), oncological treatment, specifically chemotherapy, and psychological conditions such as stress, precipitate sleep disorders.
Conclusions: There is evidence of a bidirectional correlation between cancer and sleep. Promoting healthy sleep habits can contribute to preventing the development and progression of cancer, and to improving the perception of quality of life among patients with malignant diseases.
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