Chronic Kidney Disease in Agricultural Communities, review of the literature
DOI:
https://doi.org/10.17533/udea.iatreia.136Keywords:
renal insufficiency, chronic, kidney diseases, epidemiology, renal insufficiency, nephritis, interstitial, rural population, public healthAbstract
Chronic kidney disease (CKD) is defined as an abnormality of the kidney structure or function for ≥ 3 months. This disease affects 10% to 15% of the world’s population, with diabetes, arterial hypertension, primary glomerulopathies and genetic disorders being the most common etiologies associated with this disease worldwide. Nevertheless, in low-income countries, other diseases causing CKD are also reported; among them, Mesoamerican nephropathy, which is a common cause of CKD in Mesoamerica, especially in the young male population, leading to loss of productive working capacity. In Colombia, the prevalence of CKD with unknown etiology is high and there are few studies on chronic kidney disease in agricultural communities, given that the agricultural population in Colombia is exposed to harmful climatic and ccupational agents similar to those in Mesoamerica, it is possible that this nephropathy is also a cause of CKD in our population. This article provides an overview of CKD in agricultural communities to sensitize health workers to the importance of screening for this disease in vulnerable populations, which could have a positive impact on the health of farmers.
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References
(1) Lopera-Medina M. Chronic Kidney Disease in Colombia: Health Needs and Response of the General System of Social Security in Health. Rev Gerenc Polít Salud. 2016;15(30):212-33.
(2) Romagnani P, Remuzzi G, Glassock R, Levin A, Jager KJ, Tonelli M, et al. Chronic kidney disease. Nat Rev Dis Primers. 2017;3:17088. DOI 10.1038/nrdp.2017.88.
(3) Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. Lancet. 2017 Mar 25;389(10075):1238-1252. DOI 10.1016/S0140-6736(16)32064-5.
(4) Tomlinson L, Wheeler D. Clinical evaluation and management of chronic kidney disease. In: Elsevier. Comprehensive Clinical Nephrology. 6 ed. España; Elsevier; 2019. p. 935-41.
(5) Correa-Rotter R, Garcia-Trabanino R. Mesoamerican Nephropathy. Semin Nephrol. 2019;39(3):263-71. DOI 10.1016/j.semnephrol.2019.02.004.
(6) Trabanino RG, Aguilar R, Silva CR, Mercado MO, Merino RL. [End-stage renal disease among patients in a referral hospital in El Salvador]. Rev Panam Salud Publica. 2002;12(3):202-6. DOI 10.1590/s1020-49892002000900009.
(7) Correa-Rotter R, Wesseling C, Johnson RJ. CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy. Am J Kidney Dis. 2014;63(3):506-20. DOI 10.1053/j.ajkd.2013.10.062.
(8) Gonzalez-Quiroz M, Smpokou ET, Pearce N, Caplin B, Nitsch D. Identification of young adults at risk of an accelerated loss of kidney function in an area affected by Mesoamerican nephropathy. BMC Nephrol. 2019;20(1):21. DOI 10.1186/s12882-018-1193-x.
(9) Hoy W, Ordunez P. Epidemic of Chronic Kidney Disease in Agricultural Communities in Central America. Case definitions, methodological basis and approaches for public health surveillance [internet]. Iris: Pan American Health Organization; 2017. [Consultado 2021 Ago 04]. Disponible en: https://iris.paho.org/handle/10665.2/34132
(10) García CJ. Nefropatía mesoamericana: enfermedad renal de las comunidades agrícolas de Centroamérica. Rev Ces Med. 2019;33(2):153-63.
(11) Ramon-Garcia T, Cerdas M, Madero M, Jakobsson K, Barnoya J, Crowe J, et al. Mesoamerican nephropathy: Brief review based on the Second Workshop of the Consortium for the study of the Epidemic of Nephropathy in Central America and Mexico (CENCAM). Nefrología Latinoamericana. 2017;14(1):39-45. DOI 10.1016/j.nefrol.2016.11.001.
(12) Aroca-Martinez G, Cadena-Bonfanti A. Buscan los primeros casos de nefropatía mesoamericana en Colombia [internet]. [Consultado: 2021 Ago 04]. Disponible en: https://bit.ly/2VlOWUw
(13) Wesseling C, Crowe J, Hogstedt C, Jakobsson K, Lucas R, Wegman DH. The epidemic of chronic kidney disease of unknown etiology in Mesoamerica: a call for interdisciplinary research and action. Am J Public Health. 2013;103(11):1927-30. DOI 10.2105/AJPH.2013.301594.
(14) Wijkstrom J, Leiva R, Elinder CG, Leiva S, Trujillo Z, Trujillo L, et al. Clinical and pathological characterization of Mesoamerican nephropathy: a new kidney disease in Central America. Am J Kidney Dis. 2013;62(5):908-18. DOI 10.1053/j.ajkd.2013.05.019.
(15) Ordunez P, Nieto FJ, Martinez R, Soliz P, Giraldo GP, Mott SA, et al. Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: clues to an epidemic of chronic interstitial nephritis of agricultural communities. J Epidemiol Community Health. 2018;72(4):280-6. DOI 10.1136/jech-2017-210023.
(16) Valcke M, Levasseur ME, Soares da Silva A, Wesseling C. Pesticide exposures and chronic kidney disease of unknown etiology: an epidemiologic review. Environ Health. 2017;16(1):49. DOI 10.1186/s12940-017-0254-0.
(17) Crowe J, Wesseling C, Solano BR, Umana MP, Ramirez AR, Kjellstrom T, et al. Heat exposure in sugarcane harvesters in Costa Rica. Am J Ind Med. 2013;56(10):1157-64. DOI 10.1002/ajim.22204.
(18) Herrera R, Orantes CM, Almaguer M, Alfonso P, Bayarre HD, Leiva IM, et al. Clinical characteristics of chronic kidney disease of nontraditional causes in Salvadoran farming communities. MEDICC Rev. 2014;16(2):39-48.
(19) Johnson RJ, Wesseling C, Newman LS. Chronic Kidney Disease of Unknown Cause in Agricultural Communities. N Engl J Med. 2019;380(19):1843-52. DOI 10.1056/NEJMra1813869.
(20) Crowe J, Wesseling C, Robles-Ramírez A. Mesoamerican Nephropathy: Report from the First International Research Workshop on Mesoamerican nephron. Central American Institute for Studies on Toxic Substances (IRE-UNA) and Program on Work, Environment and Health in Central America (SALTRA) [Internet]. [Consultado 2021 Ago 04]. Disponible en: https://bit.ly/3lB1an1
(21) Garcia-Trabanino R, Jarquin E, Wesseling C, Johnson RJ, Gonzalez-Quiroz M, Weiss I, et al. Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador--A cross-shift study of workers at risk of Mesoamerican nephropathy. Environ Res. 2015;142:746-55. DOI 10.1016/j.envres.2015.07.007.
(22) Lopez-Marin L, Chavez Y, Garcia XA, Flores WM, Garcia YM, Herrera R, et al. Histopathology of chronic kidney disease of unknown etiology in Salvadoran agricultural communities. MEDICC Rev. 2014;16(2):49-54.
(23) Jha V, Wang AY, Wang H. The impact of CKD identification in large countries: the burden of illness. Nephrol Dial Transplant. 2012;27 Suppl 3:iii32-8. DOI 10.1093/ndt/gfs113.
(24) Santos UP, Zanetta DM, Terra-Filho M, Burdmann EA. Burnt sugarcane harvesting is associated with acute renal dysfunction Kidney Int. 2015;87(4):792-9. DOI 10.1038/ki.2014.306.
(25) Glushakova O, Kosugi T, Roncal C, Mu W, Heinig M, Cirillo P, et al. Fructose induces the inflammatory molecule ICAM-1 in endothelial cells. J Am Soc Nephrol. 2008;19(9):1712-20. DOI 10.1681/ASN.2007121304.
(26) Cirillo P, Gersch MS, Mu W, Scherer PM, Kim KM, Gesualdo L, et al. Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. J Am Soc Nephrol. 2009;20(3):545-53. DOI 10.1681/ASN.2008060576.
(27) Lanaspa MA, Sanchez-Lozada LG, Choi YJ, Cicerchi C, Kanbay M, Roncal-Jimenez CA, et al. Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructosedependent and -independent fatty liver. J Biol Chem. 2012;287(48):40732-44. DOI 10.1074/jbc.M112.399899.
(28) Roncal Jimenez CA, Ishimoto T, Lanaspa MA, Rivard CJ, Nakagawa T, Ejaz AA, et al. Fructokinase activity mediates dehydration-induced renal injury. Kidney Int. 2014;86(2):294-302. DOI 10.1038/ki.2013.492.
(29) Suliman ME, Johnson RJ, Garcia-Lopez E, Qureshi AR, Molinaei H, Carrero JJ, et al. J-shaped mortality relationship for uric acid in CKD. Am J Kidney Dis. 2006;48(5):761-71. DOI 10.1053/j.ajkd.2006.08.019.
(30) Sánchez-Lozada LG, Tapia E, Santamaria J, Ávila-Casado C, Soto V, Nepomuceno T, et al. Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats. Kidney Int. 2005;67(1):237-47. DOI 10.1111/j.1523-1755.2005.00074.x.
(31) Kang DH, Nakagawa T, Feng L, Watanabe S, Han L, Mazzali M, et al. A role for uric acid in the progression of renal disease. J Am Soc Nephrol. 2002;13(12):2888-97. DOI 10.1097/01.asn.0000034910.58454.fd.
(32) Johnson RJ, Rodriguez-Iturbe B, Roncal-Jimenez C, Lanaspa MA, Ishimoto T, Nakagawa T, et al. Hyperosmolarity drives hypertension and CKD--water and salt revisited. Nat Rev Nephrol. 2014;10(7):415-20. DOI 10.1038/nrneph.2014.76.
(33) Jayasumana C, Gunatilake S, Senanayake P. Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka? Int J Environ Res Public Health. 2014;11(2):2125-47. DOI 10.3390/ijerph110202125.
(34) Weaver VM, Fadrowski JJ, Jaar BG. Global dimensions of chronic kidney disease of unknown etiology (CKDu): a modern era environmental and/or occupational nephropathy? BMC Nephrol. 2015;16:145. DOI 10.1186/s12882-015-0105-6.
(35) Jayasumana C, Orantes C, Herrera R, Almaguer M, Lopez L, Silva LC, et al. Chronic interstitial nephritis in agricultural communities: a worldwide epidemic with social, occupational and environmental determinants. Nephrol Dial Transplant. 2017;32(2):234-41. DOI 10.1093/ndt/gfw346.
(36) Wijetunge S, Ratnatunga NV, Abeysekera TD, Wazil AW, Selvarajah M. Endemic chronic kidney disease of unknown etiology in Sri Lanka: Correlation of pathology with clinical stages. Indian J Nephrol. 2015;25(5):274-80. DOI 10.4103/0971-4065.145095.
(37) Correa R, Garcia T. Nefropatía mesoamericana: una nueva enfermedad renal crónica de alta relevancia regional. Acta Med. 2018;16:16-22.
(38) Sanchez Polo V, Garcia-Trabanino R, Rodriguez G, Madero M. Mesoamerican Nephropathy (MeN): What We Know so Far. Int J Nephrol Renovasc Dis. 2020;13:261-72. DOI 10.2147/IJNRD.S270709.
(39) Wijkstrom J, Gonzalez-Quiroz M, Hernandez M, Trujillo Z, Hultenby K, Ring A, et al. Renal Morphology, Clinical Findings, and Progression Rate in Mesoamerican Nephropathy. Am J Kidney Dis. 2017;69(5):626-36. DOI 10.1053/j.ajkd.2016.10.036.
(40) Ferreiro A, Alvarez-Estevez G, Cerdas-Calderon M, Cruz-Trujillo Z, Mena E, Reyes M, et al. Confirmed clinical case of chronic kidney disease of nontraditional causes in agricultural communities in Central America: a case definition for surveillance. Rev Panam Salud Publica. 2016;40(5):301-8.
(41) Atanda A, Henry J, Samuel G, Fadiran O, Frederick C, Omole O, et al. Hyperuricemia-associated Mesoamerican Nephropathy: Case Report and Review of Literature. Cureus. 2018;10(9):e3282. DOI 10.7759/cureus.3282.
(42) Pan American Health Organization. Chronic Kidney Disease in Agricultural Communities in Central America. IRIS Institutional Repository for Information Sharing [internet]. [Consultado 2021 Ago 04]. Disponbile en: https://iris.paho.org/handle/10665.2/4718
(43) Balch O. Heat stress: the next global public health crisis? [Internet]. [Consultado: 2021 Ago 04]. Disponible en: https://bit.ly/3xjobx6
(44) Sociedad Latinoamericana de Nefrología e Hipertensión y la Fundación Mexicana del Riñon A.C. Guías Latinoamericanas de práctica clínica sobre prevención, diagnóstico y tratamiento de los estadios 1-5 de la enferemdad renal crónica. 1 ed. México: Programas Educativos, S.A; 2012.
(45) Levi M, Kjellstrom T, Baldasseroni A. Impact of climate change on occupational health and productivity: a systematic literature review focusing on workplace heat. Med Lav. 2018;109(3):163-79. DOI 10.23749/mdl.v109i3.6851.
(46) Adam-Poupart A, Smargiassi A, Busque MA, Duguay P, Fournier M, Zayed J, et al. Effect of summer outdoor temperatures on work-related injuries in Quebec (Canada). Occup Environ Med. 2015;72(5):338-45. DOI 10.1136/oemed-2014-102428.
(47) Fatima SH, Rothmore P, Giles LC, Varghese BM, Bi P. Extreme heat and occupational injuries in different climate zones: A systematic review and metaanalysis of epidemiological evidence. Environ Int. 2021;148:106384. DOI 10.1016/j.envint.2021.106384.
(48) Adam-Poupart A, Smargiassi A, Busque MA, Duguay P, Fournier M, Zayed J, et al. Summer outdoor temperature and occupational heat-related illnesses in Quebec (Canada). Environ Res. 2014;134:339-44. DOI 10.1016/j.envres.2014.07.018.
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