OXIDATIVE STRESS CARACTERIZATION IN STREPTOZOTOCIN-DIABETIC WISTAR RATS

Authors

  • Ángela C. MORA H. Departamento de Farmacia. Universidad Nacional de Colombia-Sede Bogotá.
  • Diana M. ARAGÓN N. Departamento de Farmacia. Universidad Nacional de Colombia-Sede Bogotá.
  • Luis F. OSPINA G. Departamento de Farmacia. Universidad Nacional de Colombia-Sede Bogotá.

Keywords:

experimental diabetes mellitus, oxidative stress.

Abstract


Diabetes is a chronic metabolic disease. Numerous studies have demonstrated that diabetes mellitus is associated to free radicals increase derived from oxygen and to the organism potential antioxidant decrease generating oxidative damage of some cell components like proteins, nucleic acids, carbohydrates and lipids. After 20 days of administration of streptozotocin in Wistar rats, we have found a relationship between levels of blood glucose and some markers from antioxidant status. We evaluate oxidative stress markers like catalasa and superoxide dismutase acivities, ferric reducing ability of plasma and thiobarbituric acid reactive species.
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Published

2009-11-23

How to Cite

MORA H., Ángela C., ARAGÓN N., D. M., & OSPINA G., L. F. (2009). OXIDATIVE STRESS CARACTERIZATION IN STREPTOZOTOCIN-DIABETIC WISTAR RATS. Vitae, 16(3), 311–319. Retrieved from https://revistas.udea.edu.co/index.php/vitae/article/view/2801

Issue

Section

Pharmacology and Toxicology

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