Trends of tuberculosis in cohorts of positives HIV patients before and after the HAART era in health institutions of Medellin (1996-2005)

Authors

  • Alexander Arbeláez University of Antioquia
  • Maria P. Arbeláez University of Antioquia
  • Rubén D. Gómez University of Antioquia
  • Carlos A. Rojas University of Antioquia
  • Sonia L. Arias University of Antioquia
  • Bibiana Castro University of Antioquia
  • Angela M. Segura University of Antioquia
  • Gloria Velásquez University of Antioquia

DOI:

https://doi.org/10.17533/udea.rfnsp.201

Keywords:

tuberculosis, trend, HAART, Colombia

Abstract

Tuberculosis (TB) is still an important disease with public health impact. Which has increased since HIV
epidemic emergence. The preventive role of highly effective antiretroviral (HAART) against TB disease is not enough to control TB because it requires regular administration and adherence to therapy. Since HAART implementation around the world, de TB, co morbidity has decreased, but is no the only factor to control it. Objectives: to determine TB trend in HIV infected patients, during HAART implementation in two patient cohorts coming from different health centers of Medellín. Methods: a descriptive study was conducted based on registries and data bases from a referral program to care HIV/AIDS patiens in different health centers in the city during 1996 to 2002, and a retrospective cohort of HIV patients with data from clinical registries which was comprised in order to compare TB risk in a prophylaxis study during 2003-2005. Results: we report an increasing trend of HAART therapy use during the period of study, with 60% of HIV patients with irregular therapy during the last period (2003-2005). The annual TB incidence was between  0.1 to 5.1%. TheTB proportion among the HIV patients who did not received haart effectiviness was 60% (RR=0.4). Conclusion: HAART therapy must be administered at each HIV/AIDS patients when the risk of developing TB
is high, according to this results, HAART therapy is effective but is not the only factor to control TB in this population.
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Author Biography

Alexander Arbeláez, University of Antioquia

Professor National Faculty of Public Health

References

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Published

2008-10-23

How to Cite

1.
Arbeláez A, Arbeláez MP, Gómez RD, Rojas CA, Arias SL, Castro B, Segura AM, Velásquez G. Trends of tuberculosis in cohorts of positives HIV patients before and after the HAART era in health institutions of Medellin (1996-2005). Rev. Fac. Nac. Salud Pública [Internet]. 2008 Oct. 23 [cited 2025 Jan. 22];25(1):1-6. Available from: https://revistas.udea.edu.co/index.php/fnsp/article/view/201

Issue

Vol. 25 No. 1 (2007)

Section

Research

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