Risk factors for germinal matrix hemorrhage in preterm infants

Abstract

To facilitate clinical diagnosis of germinal matrix hemorrhage In preterm infants, a study of cases {n: 56) and controls {n: 66) was carried out. Association was investigated between hemorrhage and maternal and neonatal risk factors; also included was the correlation between such factors and seriousness of the hemorrhagic episode. No correlation was found between maternal risk factors and hemorrhage or its seriousness. Concerning neonatal risks, gestational age under 31 weeks, the use of mechanical ventilation and persistence of ductus arteriosus, independently, showed statistical correlation with the hemorrhage {p < 0.05), whereas the simultaneous presence of three or more risks correlated with intensity of hemorrhage {p < 0.05). We conclude that the abovementioned neonatal risk factors can be suggestive of the development of germinal matrix hemorrhage in preterm Infants.