HALISTANOL TRIACETATE, A DERIVATIVE OF A BIOACTIVE METABOLITE FROM COLOMBIAN MARINE SPONGE Topsentia ophiraphidites
DOI:
https://doi.org/10.17533/udea.vitae.553Keywords:
esponjas marinas, Topsentia ophiraphidites, halistanol, antimicrobiano, triacetato de halistanol, marine sponges, antimicrobial activity, halistanol triacetateAbstract
Marine sponges genus Topsentia are known as a source of interesting bioactive compounds. Here we
report the preparation of halistanol triacetate, a derivative acetylated from halistanol. Halistanol was
isolated from bioactive fraction of methanol extract from the marine sponge Topsentia ophiraphidites,
collected on Santa Marta Bay (Colombian Caribbean Sea). Halistanol triacetate is characterized from
chromatographic, spectral and chemical data. Bioactive fraction of T. ophiraphidites show in vitro activity against Staphylococcus aureus.
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